Certified Tissue Bank Specialist 2026 Complete Practice Test

In histocompatibility testing, the primary focus is on tissue type matching. This testing assesses the compatibility of donor and recipient tissues, particularly regarding the major histocompatibility complex (MHC) proteins. These proteins play a crucial role in the immune system's ability to recognize self from non-self. Accurate histocompatibility testing ensures that the transplanted tissue is less likely to be rejected by the recipient's immune system, thereby improving transplant outcomes and reducing the risk of complications.

While gene mutations, donor age factors, and recipient health status can all impact transplant success, they are not the primary focus of histocompatibility testing. Instead, the emphasis is specifically on matching the HLA (human leukocyte antigen) characteristics between donor and recipient to ensure a higher likelihood of acceptance of the transplanted tissue. This practice is essential in organ transplantation and tissue banking to enhance the success rates of procedures involving tissue grafts.