Certified Tissue Bank Specialist 2025 Complete Practice Test

Packed red blood cells (PRBCs) must be carefully included in calculations during the dilution process to ensure that the proper concentration of red blood cells is maintained in the final product. This is important for ensuring patient safety and effectiveness in transfusion medicine. When PRBCs are thawed, their volume and cellular content can change, affecting the total hemoglobin concentration. Thus, including them in dilution calculations helps healthcare professionals accurately assess the amount of PRBCs being administered and adjust dosages accordingly, ensuring the patient receives the correct therapeutic levels.

The other options do not align with the proper management of thawed products. For instance, excluding them from calculations would result in inaccurate assessments of blood product concentrations, potentially leading to inadequate or excessive transfusions. Freezing them again is not standard practice, as once thawed, PRBCs should be used or discarded within specific time frames due to risk of hemolysis and loss of viability. Refrigerating thawed products alone is insufficient, as they also need to be accurately measured and utilized based on their functionality and intended use in transfusions.